Premium Analysis: Two Molecules, 65% of Lilly's Revenue
Mounjaro and Zepbound earned $14.9 billion of Eli Lilly's $23.0 billion second-quarter 2026 revenue. What that concentration says about the GLP-1 wave and the bioeconomy.

Eli Lilly reported second-quarter 2026 revenue of $22.97 billion, up 48% from a year earlier. Two of its products, Mounjaro and Zepbound, produced $14.87 billion of that, or 65%. A year earlier the same two products made up 55%.
This briefing looks at what that concentration says about the bioeconomy: where a single drug class is pulling the whole industry's numbers.
How concentrated is Lilly's revenue?
Mounjaro and Zepbound together earned $14.9 billion in one quarter, 65% of all Lilly revenue.
Lilly revenue by product group, second quarter 2026, $ billions. Total: $22.97 billion.
Source: Eli Lilly second-quarter 2026 earnings release, SEC Form 8-K. "Six other key products" are Jaypirca, Ebglyss, Kisunla, Omvoh, Foundayo and Inluriyo. "All products not listed as key" is total revenue minus the eight key products Lilly reports.
View data
| line | revenue |
|---|---|
| Mounjaro | 9.94 |
| All products not listed as key | 7.27 |
| Zepbound | 4.93 |
| Six other key products | 0.84 |
Mounjaro earned $9.94 billion, up 91% year over year. Zepbound earned $4.93 billion, up 46%. Lilly's other six key products earned a combined $0.84 billion. Everything else, which is mostly older products, earned $7.27 billion.
The share has grown quickly. In the second quarter of 2025, Mounjaro ($5.20 billion) and Zepbound ($3.38 billion) were $8.58 billion of $15.56 billion in revenue, or 55%. For the first six months of 2026 the share is 65%, the same as the quarter: $27.69 billion of $42.77 billion.
Volume drives it. Lilly reports that total volume was up 60% in the quarter while realized prices fell 13%.
Verifying access...
Sources
- Eli Lilly, Second-quarter 2026 earnings release (Form 8-K): revenue by product, price and volume effects, and guidance.
- Eli Lilly, Form 10-Q for the quarter ended June 30, 2026: Mounjaro revenue by US and outside the US.
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